Title: An emerging paradigm in biology:  the power of weak binding

Speaker: Greg Forest（University of North Carolina--Chapel Hill, USA）

Time：2019/08/14 (Wed) 10:00-10:45

Place：工商楼200-9

Abstract: Understanding Nature’s biological design rules is essential for regenerative medicine, therapies for disease pathologies, and vaccines. Working with diverse biologists, medical and clinical scientists, we have data to guide and validate underlying biological mechanisms. One is now clear: the role of transient, short-lived, binding interactions for diverse functionalities. I will focus on dynamic organization of the genome in live cells and mucus barriers that protect all organs, and briefly describe other projects with the same paradigm. Collaborators will be acknowledged in the lecture.

Bio: Greg Forest, Grant Dahlstrom Distinguished Professor of Mathematics and founder of the applied math program at UNC-Chapel Hill. University of New Orleans, B.S. in Mathematics, 1972 and M.S. in Mathematics, 1973; University of Arizona, Ph.D. in Mathematics, 1979. The Forest Group focuses on the mathematics of, and translational applications to, multiple applied science challenges, such as lung biology and disease, virology and immunology, nanoparticle drug strategies for human cancer, chromosomal organization and dynamics in living cells, and mechano-chemical mechanisms of cell motility, We also delve into problems associated with the design and optimization of polymer nanocomposites with extreme properties, active soft matter, understanding the generic principles of soft matter, and encoding them into predictive modeling for feedback with experimental collaborators.

联系人：林智（linzhi80@zju.edu.cn）